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Laxofast
- Development stage
- Unknown
- Lead developer
- Thrift Pharmaceuticals
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Laxofast is an oral laxative suspension developed by Thrift Pharmaceuticals. It is a fixed-dose combination containing light liquid paraffin, milk of magnesia (magnesium hydroxide), and sodium picosulfate. This combination utilizes three distinct mechanisms to relieve constipation: light liquid paraffin acts as a lubricant to soften stool and ease its passage; magnesium hydroxide acts as an osmotic laxative, drawing water into the intestinal lumen to increase stool volume and stimulate peristalsis; and sodium picosulfate is a stimulant laxative that is hydrolyzed by colonic bacteria to its active metabolite, directly stimulating colonic peristalsis. Laxofast is approved and marketed for the treatment of constipation.
- Brand names
- LaxofastLaxofast-P
- Other names
- Light Liquid Paraffin, Milk of Magnesia & Sodium Picosulfate suspensionSodium Picosulfate oral solutionlight liquid paraffin + magnesium hydroxide + sodium picosulfate
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