Drug intelligence / Profile preview

LBL-003

Development stage
Phase 1
Lead developer
LEADS BioLabs
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

LBL-003 is a recombinant fully human monoclonal antibody targeting T lymphocyte immunoglobulin mucin-3 (TIM-3). It specifically binds to TIM-3 on the surface of immune cells, blocking the TIM-3 pathway and thereby restoring anti-tumor immune responses. LBL-003 is being developed as an immunotherapy for advanced malignant tumors, with its primary mechanism involving inhibition of the TIM-3 immune checkpoint to enhance T-cell mediated anti-tumor activity. The drug is currently in clinical development for patients with advanced solid tumors who have failed standard treatments or are not suitable for them.

Other names
anti-PD-1 antibody (Nanjing Leads Biolabs)anti-PD-1 antibody injectionanti-PD1 antibody injectionanti-PD 1 antibody injection
02

Targets

HAVCR2 (T cell immunoglobulin and mucin domain-containing protein 3)

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