Drug intelligence / Profile preview

LBM22

Development stage
Preclinical
Lead developer
China Pharmaceutical University
01

Overview

LBM22: sourced facts only. name: "Notably, compound LBM22 demonstrated potent inhibition of CLK2 (IC50 = 3.9 nM), leading to broad suppression of NSCLC cells proliferation and induction of apoptosis." [PMID:39406119]; target: "Notably, compound LBM22 demonstrated potent inhibition of CLK2 (IC50 = 3.9 nM), leading to broad suppression of NSCLC cells proliferation and induction of apoptosis." [PMID:39406119]; developer: "Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing, 210009, PR China." [PMID:39406119]; stage: "Additionally, significant antiproliferative activity was observed for LBM22 in 3D cultured H1975OR cells." [PMID:39406119]

02

Targets

CLK2 (CDC-like kinase 2)

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