Drug intelligence / Profile preview

LBS-002

Development stage
Preclinical
Lead developer
Lin BioScience
Modality
Small Molecules
01

Overview

LBS-002 is a small molecule drug developed as a tubulin inhibitor, designed to disrupt the division of cancer cells by preventing the formation of microtubules. It is notable for its ability to cross the blood–brain barrier, making it a promising candidate for treating brain cancers such as glioblastoma and brain metastases, where traditional treatments are often ineffective due to poor permeability. The drug was initially developed by Lin BioScience in collaboration with researchers at the University of Sydney[1][2][3].

02

Targets

TUBB (Tubulin (alpha and beta subunits))

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