Drug intelligence / Profile preview

LC Bead LUMI

Development stage
Unknown
Lead developer
Bio-Technology General
Modality
Hydrogel Systems → Drug Delivery Systems
Administration
Intra-arterial
01

Overview

LC Bead LUMI is a directly image-able, inherently radiopaque embolic agent composed of sulfonate-modified polyvinyl alcohol (PVA) hydrogel microbeads with covalently bound iodine (~260 mg I/ml). Developed by BTG (now Boston Scientific), it is designed for the transarterial embolization (TAE) of hypervascular liver tumors, including hepatocellular carcinoma (HCC) and neuroendocrine tumors. The beads provide mechanical occlusion of the blood vessels supplying the tumor, while their radiopacity allows for real-time feedback and geographic localization during the procedure using fluoroscopy, digital subtraction angiography (DSA), and cone-beam CT (CBCT). This visibility assists interventional radiologists in ensuring complete coverage of the target lesion and identifying potential areas of under-treatment.

Brand names
LC Bead LUMI
Other names
Lumi BeadsLC Bead LUMI iodinated microbeads

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