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LCAR1901 (The First Affiliated Hospital of USTC)

Development stage
Unknown
Lead developer
The First Affiliated Hospital of USTC
Modality
CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies, Gene Therapies
Administration
Intravenous
01

Overview

LCAR1901 is a Chimeric Antigen Receptor T (CAR-T) cell therapy that involves genetically modifying a patient's own T-cells to express chimeric antigen receptors (CARs). These engineered T-cells are designed to recognize and target cancer cells expressing both B-cell maturation antigen (BCMA) and CD19 proteins on their surface. This dual-targeting approach aims to provide a potent and specific treatment for relapsed and refractory blood cancers, including B-cell acute lymphoblastic leukemia, B-cell non-Hodgkin lymphoma, and immune thrombocytopenia. The therapy works by directing the modified T-cells to attack and destroy the cancer cells.

Other names
Anti-CD19/BCMA CAR Gene Vector InjectionAnti-BCMA and CD19 CARTCLIC-1901 CAR T-cell therapyCLIC1901 CAR T-cell therapyCLIC 1901 CAR T-cell therapy
02

Targets

CD19 (B lymphocyte antigen CD19)BCMA (B-cell maturation antigen)

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