Drug intelligence / Profile preview

LCB33

Development stage
Unknown
Lead developer
LigaChem Biosciences, Inc.
Modality
Small Molecules
01

Overview

LCB33: sourced facts only. name: "LCB33 ENPP1 inhibitor shows excellent ENPP1 inhibitory activity at an IC50 of 0.9pM and 1nM in enzyme assay using pNP-TMP and cGAMP as substrates, respectively." [DOI:10.1158/1538-7445.am2023-702]; target: "LCB33 ENPP1 inhibitor shows excellent ENPP1 inhibitory activity at an IC50 of 0.9pM and 1nM in enzyme assay using pNP-TMP and cGAMP as substrates, respectively." [DOI:10.1158/1538-7445.am2023-702]; developer: "1LegoChem Biosciences, Inc, Daejeon, Republic of Korea." [DOI:10.1158/1538-7445.am2023-702]; modality: "Taken together, we report a novel and potent small molecule ENPP1 inhibitor in this study." [DOI:10.1158/1538-7445.am2023-702]

02

Targets

ENPP1

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