Drug intelligence / Profile preview

LemoCalm

Development stage
Unknown
Lead developer
Bristol Laboratories
Modality
Small Molecules
Administration
Oral
01

Overview

LemoCalm is a line of over-the-counter (OTC) multi-symptom relief products developed by Bristol Laboratories for the treatment of cold, flu, and cough symptoms. The product range includes several formulations: powders for oral solution, capsules, and an oral solution. These products utilize a combination of active ingredients to target various symptoms: paracetamol acts as an analgesic and antipyretic by indirectly inhibiting cyclooxygenase (COX) enzymes; phenylephrine hydrochloride serves as a nasal decongestant through alpha-1 adrenergic receptor agonism; caffeine is included in some formulations as a stimulant and analgesic adjuvant; and dextromethorphan hydrobromide acts as an antitussive for dry cough, putatively through sigma-1 and NMDA receptors. The line is designed to provide symptomatic relief from pain, fever, nasal congestion, and non-productive cough associated with upper respiratory tract infections.

Brand names
LemoCalm Max Strength Cold and Flu Relief PowderLemoCalm Cold and Flu Relief PowderLemoCalm PLUS Cold and Flu CapsulesLemoCalm Dry Cough Oral Solution
Other names
LemoCalm Max Strength Cold and Flu Relief Powder (Paracetamol/Phenylephrine) 1000 mg / 10 mgLemoCalm Cold and Flu Relief Powder (Paracetamol/Phenylephrine) 650 mg / 10 mgLemoCalm PLUS Cold and Flu Capsules (Paracetamol/Caffeine/Phenylephrine) 300 mg / 25 mg / 5 mgLemoCalm Dry Cough Oral Solution (Dextromethorphan Hydrobromide) 10 mg / 5 ml
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)ADRA1A (α1A)PGHS-1 (Prostaglandin G/H Synthase 1)

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