LEO 130852A placebo gel

LEO 130852A placebo gel is the inactive vehicle formulation used as a control in clinical trials evaluating **LEO 130852A**, an experimental topical agent developed by **LEO Pharma**. The active compound, LEO 130852A, is being investigated for its potential to mitigate or prevent **steroid-induced skin atrophy**, a common side effect of chronic topical corticosteroid use characterized by thinning of the dermal and epidermal layers. In clinical studies, such as the Phase I trial NCT03811028, the placebo gel is applied to healthy skin alongside the active drug and a potent corticosteroid (clobetasol propionate) to assess the specific efficacy of the active ingredient in maintaining skin thickness and integrity. As a placebo, it contains the same excipients and physical properties as the active gel but lacks the therapeutic active pharmaceutical ingredient.

Other names

Placebo gel for LEO 130852AVehicle gel for LEO 130852A