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LEO 134310 vehicle
- Development stage
- Unknown
- Lead developer
- LEO Pharma
- Administration
- Topical
01
Overview
LEO 134310 vehicle is the pharmacologically inactive cutaneous solution used as a placebo control in clinical trials for LEO 134310. LEO 134310, developed by LEO Pharma, is a non-steroidal, selective glucocorticoid receptor (GR) agonist designed as a "dual-soft" ligand that is rapidly deactivated in the blood and liver to minimize systemic side effects. The vehicle formulation is used in Phase 1 studies to provide a baseline for evaluating the safety, tolerability, and efficacy of the active compound in patients with chronic plaque psoriasis. It is designed to match the physical and delivery characteristics of the active drug without containing the active pharmaceutical ingredient.
- Brand names
- LEO 134310 vehicleLEO134310 vehicleLEO-134310 vehicle
- Other names
- LEO 134310 vehicle-LEO Pharma-psoriasis (chronic plaque)
02
Targets
GR (Glucocorticoid receptor)
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