leptochloa fusca extract

Leptochloa fusca extract is an aqueous preparation derived from the shoot systems of the perennial grass *Leptochloa fusca*, commonly known as Sprangletop. It is characterized by a rich phytochemical profile containing phenols, flavonoids, alkaloids, tannins, saponins, and steroids. Preclinical research indicates that the extract possesses significant antioxidant, antiparasitic, antibacterial, and anticancer properties. Its anticancer mechanism of action involves the induction of apoptosis through the disruption of mitochondrial membrane potential, leading to cytochrome c release and subsequent caspase activation. In bacterial pathogens, it exhibits antibacterial effects by causing DNA damage and increasing plasma membrane permeability. The extract has shown in vitro efficacy against various parasites (e.g., *Plasmodium falciparum*), carcinogenic bacteria (e.g., *Helicobacter pylori*), and multiple cancer cell lines including gastric, pancreatic, and breast cancers.

Other names

Sprangletop extractDiplachne fusca extractLeptochloa fusca aqueous extract