Drug intelligence / Profile preview

Leugon

Development stage
Approved
Lead developer
AMW
Modality
Peptides
Administration
Subcutaneous
01

Overview

Leugon is a biodegradable subcutaneous implant containing leuprorelin acetate, a gonadotropin-releasing hormone (GnRH) agonist. Developed by AMW GmbH and marketed by its subsidiary Endomedica, it is specifically indicated for the symptomatic treatment of advanced hormone-dependent prostate cancer. The drug works by initially stimulating and subsequently downregulating GnRH receptors in the pituitary gland, leading to a profound reduction in the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This results in the suppression of testosterone production to castrate levels, thereby inhibiting the growth of hormone-sensitive prostate tumors. The product is supplied as a ready-to-use prefilled syringe containing an 11.25 mg implant, designed for sustained release over several months without the need for reconstitution steps prior to application.

Brand names
Leugon
Other names
leuprorelin acetate implantLeugon 11.25 mg Fertigspritze mit ImplantatLeugon11.25 mg Fertigspritze mit ImplantatLeugon-11.25 mg Fertigspritze mit Implantat
02

Targets

GnRHR (Gonadotropin-releasing hormone receptor)

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