leuprolide acetate + isopropyl alcohol

Leuprolide acetate + isopropyl alcohol is a pharmaceutical kit marketed by Sandoz, consisting of a multi-dose vial of leuprolide acetate for injection and 70% isopropyl alcohol medicated pads for site preparation. Leuprolide acetate is a synthetic nonapeptide analogue of naturally occurring gonadotropin-releasing hormone (GnRH). It functions as a potent GnRH receptor agonist; while initial administration causes a transient increase in circulating levels of luteutizing hormone (LH) and follicle-stimulating hormone (FSH), continuous administration leads to the downregulation of GnRH receptors. This results in the suppression of gonadotropin secretion and a subsequent reduction in ovarian and testicular steroidogenesis to castrate or postmenopausal levels. The isopropyl alcohol component serves as a topical antiseptic to minimize the risk of infection at the subcutaneous injection site. This specific formulation is primarily utilized for the palliative treatment of advanced prostate cancer.

Other names

leuprolide acetate kitleuprorelin acetate + isopropyl alcoholleuprolide acetate + 70% isopropyl alcohol pad