Drug intelligence / Profile preview

Levera

Development stage
Unknown
Lead developer
Intas Pharmaceuticals
Modality
Small Molecules
Administration
Oral, Intravenous
01

Overview

Levera is an anti-epileptic medication developed and marketed by Intas Pharmaceuticals, containing the active ingredient levetiracetam. As a small molecule drug, it is indicated for the treatment of various seizure types in patients with epilepsy, including partial-onset, myoclonic, and tonic-clonic seizures. Its primary mechanism of action involves binding to the synaptic vesicle protein 2A (SV2A), which is thought to modulate the release of neurotransmitters and reduce hypersynchronous neuronal firing. Additionally, it has been shown to inhibit N-type voltage-gated calcium channels. Levera is available in several formulations, such as immediate-release tablets, extended-release tablets (Levera XR), oral solutions, and injectable forms, allowing for flexible dosing as either monotherapy or adjunctive treatment in both pediatric and adult populations.

Brand names
LeveraLevera XR
Other names
levetiracetam
02

Targets

CACNA1B (Voltage-dependent N-type calcium channel subunit alpha-1B)SV2A (Synaptic vesicle glycoprotein 2A)

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