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levo-demethylphencynonate hydrochloride
- Development stage
- Unknown
- Lead developer
- Academy of Military Medical Sciences
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Levo-demethylphencynonate hydrochloride is a small molecule muscarinic acetylcholine receptor antagonist developed by the Institute of Toxicology and Pharmacology at the Academy of Military Medical Sciences in China. It is the levo-isomer of demethylphencynonate, which is itself a derivative of the anticholinergic drug phencynonate. The compound is primarily being investigated for the treatment of Parkinson's syndrome, where it is intended to alleviate motor symptoms by inhibiting overactive cholinergic signaling in the central nervous system. Clinical development has progressed through Phase 1 trials in China, focusing on the safety, tolerability, and pharmacokinetics of the drug in healthy volunteers.
- Other names
- L-demethylphencynonate hydrochloride(-)-demethylphencynonate hydrochloride
02
Targets
mAChR (Muscarinic acetylcholine receptors)
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