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levomefolic acid
- Development stage
- Unknown
- Lead developer
- Alico Pharmaceutical
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Efafol is a nutraceutical supplement developed by Alico Pharmaceutical containing levomefolic acid (L-methylfolate). As the primary biologically active form of folate, levomefolic acid is essential for the conversion of homocysteine to methionine and the synthesis of DNA and RNA. Unlike synthetic folic acid, it does not require enzymatic conversion by methylenetetrahydrofolate reductase (MTHFR), making it particularly beneficial for individuals with MTHFR genetic polymorphisms. It is commonly used to support prenatal health, manage folate deficiency, and as an adjunct in the treatment of depression.
- Brand names
- Efafol
- Other names
- EfafolL-methylfolate5-methyltetrahydrofolate5-MTHFlevomefolic acidL-Methylefolate
02
Targets
MTR (5-methyltetrahydrofolate-homocysteine methyltransferase)
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