Drug intelligence / Profile preview

Levopront

Development stage
Phase 3
Lead developer
Dompé
Modality
Small Molecules
Administration
Oral
01

Overview

**Levopront** is a brand name for levodropropizine, a peripherally acting antitussive agent used for the symptomatic treatment of non-productive (dry) cough in adults and children over 2 years or weighing more than 30 kg. It exhibits both antitussive and bronchodilatory effects through modulation of sensory neuropeptides in the respiratory tract, inhibiting neuropeptide release from C-fibers in airway sensory nerves without central nervous system depression or opioid-related side effects like constipation or respiratory depression. Developed by Dompé farmaceutici and available as 60 mg tablets or 30 mg/5 mL syrup, it is indicated for cough associated with upper/lower respiratory infections, lung cancer, or whooping cough, with dosing of 60 mg three times daily for up to 7 days orally.[1][2][7][9][12]

Brand names
Levopront
02

Targets

H (Histamine receptors)NaV (Voltage-gated sodium channels)TRPV1 (Transient receptor potential cation channel subfamily V member 1)

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