Drug intelligence / Profile preview

LHNVD-201

Development stage
Preclinical
Lead developer
Longhorn Vaccines and Diagnostics
Modality
Peptides, Vaccines & Immunotherapeutics
01

Overview

**LHNVD-201** is a preclinical unconjugated synthetic peptide vaccine candidate developed by Longhorn Vaccines and Diagnostics to prevent COVID-19, influenza, and their co-infections. The vaccine incorporates highly conserved epitopes from influenza neuraminidase and matrix proteins M1/M2, together with SARS-CoV-2 spike protein and RNA polymerase. In mouse studies, peptide formulations generated durable antibody responses and neutralizing activity against influenza viruses and SARS-CoV-2; results were presented at the 17th Vaccine Congress in Glasgow in September 2023. ([businesswire.com](https://www.businesswire.com/news/home/20230925926655/en/Longhorn-Vaccines-and-Diagnostics-Presents-Data-Demonstrating-Neutralizing-Activity-of-LHNVD-201-for-Covid-19-and-Influenza-Co-Infections))

Other names
LHNVD 201LHNVD201LHNVD-201
02

Targets

M1 (Muscarinic acetylcholine receptor M1)CHRM2 (M2)SARS-CoV-2 spikeNeuraminidase

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