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liangge powder decoction
- Development stage
- Unknown
- Lead developer
- Shuguang Hospital
- Administration
- Oral
01
Overview
Liangge Powder Decoction (Liang Ge San) is a traditional Chinese medicinal formula used to treat upper and middle burner heat syndromes. In the context of modern clinical practice, it is being investigated for its efficacy in treating sepsis-associated acute gastrointestinal injury (AGI). The formula typically consists of Forsythiae Fructus, Rhei Radix et Rhizoma, Natrii Sulfas, Glycyrrhizae Radix et Rhizoma, Gardeniae Fructus, Menthae Haplocalycis Herba, Scutellariae Radix, and Lophatheri Herba. Its mechanism involves clearing heat, detoxifying, and promoting bowel movements, which translates to anti-inflammatory effects, reduction of systemic inflammatory response syndrome (SIRS), and protection of the intestinal mucosal barrier.
- Other names
- Liangge PowderLiang Ge SanLiangge San
02
Targets
STAT3 (Signal Transducer and Activator of Transcription 3)FXR (Farnesoid x-activated receptor)IL-6 (Interleukin 6)TNFA (Tumor necrosis factor alpha (soluble))CHRNA7 (α7 nicotinic receptor)
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