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Lianpu Qingwei Granules
- Development stage
- Preclinical
- Lead developer
- Hubei Provincial Traditional Chinese Medical Hospital
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Lianpu Qingwei Granules (also known as Lianpu Qingwei Keli) is a traditional Chinese medicine (TCM) formulation developed by Hubei Provincial Hospital of Traditional Chinese Medicine. It is primarily used for the treatment of Helicobacter pylori infection and gastritis, particularly in patients presenting with spleen-stomach damp-heat syndrome. The formulation is designed to clear heat, resolve dampness, and harmonize the stomach. It has been evaluated in clinical trials as an adjunctive therapy combined with standard quadruple eradication regimens (such as rabeprazole, bismuth potassium citrate, and antibiotics) to optimize Helicobacter pylori eradication rates and improve clinical symptoms.
- Other names
- Lianpu Qingwei Keli连朴清胃颗粒
02
Targets
Mpro (3C-like proteinase of SARS-CoV-2)STAT3 (Signal Transducer and Activator of Transcription 3)IL-6 (Interleukin 6)ACE2 (Angiotensin-converting enzyme 2)
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