Lianqiao Jinbei Decoction

Lianqiao Jinbei Decoction is a traditional Chinese medicine (TCM) herbal formula used for the treatment of **HER2-positive breast cancer** and other conditions associated with internal heat and toxicity[1][7][13]. Its primary mechanism involves **multi-component, multi-target action**, where core active ingredients such as quercetin, β-sitosterol, and luteolin suppress tumor cell proliferation and migration and promote apoptosis mainly by inhibiting expression of the **HER2 protein** in HER2-positive breast cancer cells[1][11]. Network pharmacology and experimental data indicate the decoction regulates HER2 protein, leading to effective tumor suppression[1][11]. The formula is also known in TCM for **clearing heat, detoxifying, reducing swelling, and invigorating the blood**[7][9]. It is used in practice for conditions such as sores, abscesses, and Yang toxicity with internal heat[7][13]. Lianqiao Jinbei Decoction is customarily prepared from a combination of herbs and administered as an oral decoction. Its principal indications in research are HER2-positive breast cancer and symptoms of internal heat/toxicity.

Other names

LJDLian Qiao Jin Bei JianLianqiao Jinbei