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Lianxia Ningxin Granules
- Development stage
- Preclinical
- Lead developer
- Beijing University of Chinese Medicine Third Affiliated Hospital
- Administration
- Oral
01
Overview
Lianxia Ningxin Granules (连夏宁心颗粒) is a traditional Chinese medicine (TCM) hospital preparation developed and used in China, primarily as an in-hospital formulation. It is designed for cardiovascular indications, with clinical research focused on its effects in conditions such as myocardial infarction and potentially other heart-related diseases. The granule formulation is based on the "Lianxia Ningxin" prescription, which typically combines multiple herbal ingredients to exert synergistic effects such as improving blood circulation, protecting cardiac tissue, and modulating inflammation or oxidative stress. The exact mechanism of action depends on the specific herbal components but generally involves multi-target modulation typical of TCM formulas[2][7].
- Brand names
- Lianxia Ningxin Granules
- Other names
- 连夏宁心颗粒
02
Targets
NOS3 (eNOS)NPPA (Atrial natriuretic peptide precursor)NGF (Nerve growth factor)VEGFA (Vascular endothelial growth factor A)CRH (Corticotropin-Releasing Factor)ADIPOQ (Adiponectin)TGFB (GARP–latent transforming growth factor beta 1 complex)CXCL12 (C-X-C motif chemokine ligand 12)MAPK3 (Mitogen-activated protein kinase 1)IL-6 (Interleukin 6)
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