licochalcone A + decanediol + L-carnitine + salicylic acid

This combination is a topical dermatological formulation primarily developed by Beiersdorf for the treatment of acne-prone skin. It utilizes a multi-modal approach to address the four key factors of acne: hyperkeratosis, seborrhea, microbial colonization, and inflammation. Salicylic acid acts as a keratolytic agent to unclog pores and reduce blemishes; L-carnitine regulates sebum production by promoting fatty acid oxidation within sebocytes; Decanediol (1,2-decanediol) provides targeted antibacterial activity against *Cutibacterium acnes*; and Licochalcone A, a flavonoid derived from licorice root (*Glycyrrhiza inflata*), serves as a potent anti-inflammatory and antioxidant agent to soothe irritation and reduce redness. The formulation is designed to improve skin clarity and texture while minimizing the risk of irritation often associated with intensive acne treatments.

Brand names

Eucerin DermoPurifyer Oil Control Skin Renewal TreatmentEucerin DermoPure Skin Renewal Treatment