Drug intelligence / Profile preview

licorice + lotus root powder + amoxicillin

Development stage
Unknown
Modality
Small Molecules
Administration
Oral
01

Overview

A combination therapy that pairs low-dose amoxicillin (an antibiotic) with licorice and lotus root powder for the treatment of Helicobacter pylori infection. Amoxicillin is an aminopenicillin antibiotic that inhibits bacterial cell wall synthesis. Glycyrrhizin, the main active component in licorice, demonstrates antibacterial properties by inhibiting bacterial growth through targeting bacterial enzymes, affecting cell membrane formation, and altering membrane permeability. It also has anti-inflammatory and immunomodulatory effects. The combination approach may help reduce the required dose of amoxicillin while maintaining efficacy against H. pylori.

Other names
Low-Dose Amoxicillin Dual-Therapy Combined with Licorice and Lotus Root Powder Helicobacter Pylori Treatment
02

Targets

PBP (Penicillin-binding protein family)

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