Drug intelligence / Profile preview

lidocaine + morphine

Development stage
Unknown
Lead developer
EpiCept
Modality
Small Molecules
Administration
Intravenous, Intrathecal
01

Overview

Lidocaine + morphine is a drug combination used for pain management. This combination leverages the complementary mechanisms of action of both drugs to provide enhanced analgesia. Lidocaine is a local anesthetic that works by blocking sodium channels in sensory nerve fibers, inhibiting the production or conduction of electrical impulses. Morphine is a narcotic analgesic (opioid) that acts on the central nervous system to relieve pain. When administered together, these drugs have been shown to synergistically potentiate each other's antinociceptive effects, particularly for post-operative pain management and during surgical procedures.

Other names
morphine-lidocainelidocaine-morphineMLK combination
02

Targets

NaV (Voltage-gated sodium channels)DOR (Opioid Receptor Delta 1)MOR (Mu opioid receptor)

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