Drug intelligence / Profile preview

lidocaine + prilocaine (Akrikhin)

Development stage
Unknown
Lead developer
Akrikhin
Modality
Small Molecules
Administration
Topical
01

Overview

Acriol Pro is a topical anesthetic cream containing a eutectic mixture of lidocaine (2.5%) and prilocaine (2.5%). Developed and manufactured by the Russian pharmaceutical company Akrikhin, it is a generic version of Emla. Acriol Pro is indicated for surface anesthesia of the skin and genital mucosa prior to painful dermatological, cosmetic, and minor surgical procedures, such as injections, vaccinations, catheterization, and epilation. The combination of lidocaine and prilocaine acts synergistically to block voltage-gated sodium channels in the neuronal membrane, preventing the generation and conduction of nerve impulses to provide effective local pain relief.

Brand names
Acriol Pro
Other names
Acryol Prolidocaine/prilocaine
02

Targets

SCN5A (Sodium channel protein type 5 subunit alpha)

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