lidocaine + tetracaine

Lidocaine + tetracaine is a fixed-dose combination of two local anesthetics used topically to numb the skin before minor medical or cosmetic procedures, such as blood draws, IV insertions, skin biopsies, laser treatments, dermal filler injections, and tattoo removal[1][3][4][5]. Both components act by blocking sodium channels in neuronal membranes (sodium channel antagonists), thereby inhibiting nerve impulse conduction and producing localized loss of sensation without causing unconsciousness[1][6]. The combination is available as a prescription-only cream or patch. It was originally developed by ZARS and has been further developed or marketed by companies including Crescita Therapeutics, Galderma, and Nuvo Research[6].

Brand names

SyneraPliaglisNynutey CreamNoliraFlexicaineS-Caine Peel

Other names

lidocaine and tetracaine topical creamtetracaine/lidocaine topical cream