Drug intelligence / Profile preview

lidocaine + vasopressin

Development stage
Unknown
Modality
Small Molecules
Administration
Local Injection
01

Overview

A combination of lidocaine and vasopressin used primarily for local anesthesia. Lidocaine acts as a local anesthetic by blocking sodium channels in nerve membranes, preventing the initiation and conduction of nerve impulses. Vasopressin causes vasoconstriction, which reduces local blood flow at the injection site. This reduction in blood flow decreases the rate at which lidocaine is removed from the area, promoting localization and retention of lidocaine in target tissues and extending the duration of anesthesia without significantly affecting overall circulatory dynamics.

02

Targets

SCN5A (Sodium channel protein type 5 subunit alpha)AVPR2 (Arginine vasopressin V2 receptor)AVPR1B (Vasopressin V1b Receptor)AVPR1A (Arginine vasopressin receptor 1A)

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