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lidocaine hydrochloride + isopropyl alcohol + methylprednisolone
- Development stage
- Unknown
- Lead developer
- Pfizer
- Modality
- Small Molecules
- Administration
- Intramuscular, Intraarticular, Intralesional, Parenteral
01
Overview
This entry refers to a **combination formulation** containing **lidocaine hydrochloride**, **isopropyl alcohol**, and **methylprednisolone**. Pharmacologically, lidocaine is a local anesthetic that blocks voltage-gated sodium channels to reduce nerve conduction and provide local analgesia, while methylprednisolone is a glucocorticoid receptor agonist that suppresses inflammatory gene transcription and downstream immune signaling. Isopropyl alcohol in such a formulation would generally function as a solvent, vehicle, or antiseptic excipient rather than a primary therapeutic active ingredient. The supplied source text specifically documents public indications for **methylprednisolone acetate injectable suspension** and **DEPO-MEDROL**, but does **not** provide a concrete public-source verification of the exact three-component product \"lidocaine hydrochloride + isopropyl alcohol + methylprednisolone\" as a distinct branded or development-stage drug asset. Therefore, this annotation treats the queried item as an exact named combination of known pharmaceutical substances, but with limited evidence that this precise combination is a separately verified product in public development or regulatory sources.
- Other names
- lidocaine hydrochloride + isopropyl alcohol + methylprednisolone
02
Targets
GR (Glucocorticoid receptor)NaV (Voltage-gated sodium channels)
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