Drug intelligence / Profile preview

lidocaine hydrochloride + isopropyl alcohol + methylprednisolone acetate + povidone-iodine

Development stage
Unknown
Lead developer
Asclemed USA
Modality
Small Molecules
Administration
Intramuscular, Intraarticular, Intralesional, Parenteral, Topical
01

Overview

Lidocaine hydrochloride + isopropyl alcohol + methylprednisolone acetate + povidone-iodine is an Rx-only combination injection kit marketed under the Dyural L Kit brand family. The therapeutically relevant component is **methylprednisolone acetate**, a depot synthetic glucocorticoid corticosteroid suspension used for intramuscular, intra-articular, soft tissue, and intralesional administration to deliver anti-inflammatory and immunosuppressive effects primarily through activation of the glucocorticoid receptor. **Lidocaine hydrochloride** provides local anesthetic activity, while **povidone-iodine** and **isopropyl alcohol** function as antiseptic skin-preparation components included in the kit rather than core systemic therapeutic agents. The kit has been listed in DailyMed as an unapproved drug product whose labeling has not been approved by the FDA, and it is associated with broad labeled corticosteroid uses across allergic, rheumatologic, dermatologic, hematologic, endocrine, neurologic, pulmonary, renal, gastrointestinal, ophthalmic, and soft-tissue inflammatory conditions.

Brand names
Dyural L Kit
02

Targets

GR (Glucocorticoid receptor)NaV (Voltage-gated sodium channels)

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