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lidocaine liposomal
- Development stage
- Phase 4
- Lead developer
- RGR Pharma
- Modality
- Small Molecules, Liposomes → Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems
- Administration
- Topical
01
Overview
Lidocaine liposomal is a specialized drug delivery formulation that encapsulates lidocaine within liposomes to enhance its therapeutic effects and delivery characteristics. This formulation offers several advantages over conventional lidocaine preparations. The liposome encapsulation protects the anesthetic from being metabolized too quickly, providing a more sustained release. It offers advantages including "needle-free" administration, shorter onset of action, and minimal vasoactive properties that reduce interference with procedures like cannulation. Unlike some other topical anesthetics such as lidocaine-prilocaine (EMLA), it is not associated with methemoglobinemia. Lidocaine itself works as a local anesthetic by blocking nerve signals at nerve endings in the skin, causing temporary loss of feeling in the application area.
- Brand names
- Maxilene
- Other names
- liposome-encapsulated lidocaineliposomal lidocaine
02
Targets
NaV (Voltage-gated sodium channels)
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