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Lifei Qingchang Granules

Development stage: Phase 2
Lead developer: The First Affiliated Hospital of Guangzhou Medical University
Modality: Small Molecules
Administration: Oral

Overview

Lifei Qingchang Granules (LFQC) is a traditional Chinese medicine (TCM) formula developed as an in-hospital preparation by The First Affiliated Hospital of Guangzhou Medical University for the treatment of bronchiectasis. Adapted from the classic Yueju Pill and Dachaihu Decoction, the formulation consists of ten natural herbal and mineral components, including Gardenia jasminoides, Scutellaria baicalensis, and Rheum officinale. LFQC is designed to reduce airway inflammation by inhibiting the formation of neutrophil extracellular traps (NETs) and targeting the NOX2/p47phox signaling pathways. It is currently being evaluated in Phase 2 clinical trials for its efficacy in improving respiratory symptoms and quality of life in adult patients with stable bronchiectasis, as well as preventing acute exacerbations.

Other names: Lifei Qingchang GranulesLFQC

Targets

NOX2 (NADPH oxidase 2)

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