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LifePort Perfusion Solution is a specialized hypothermic machine perfusion solution used in conjunction with the LifePort Kidney Transporter system for the preservation, flushing, and transport of donor kidneys prior to transplantation. The solution is designed to maintain organs in a near-normal physiologic state under cold (2–8°C), aseptic conditions by providing essential nutrients and electrolytes while minimizing ischemic injury during storage and transport. It is typically used as part of a closed perfusion circuit that gently pumps the chilled solution through the organ, improving graft survival rates compared to static cold storage methods. The primary mechanism involves physical organ preservation via hypothermic perfusion rather than direct pharmacological action on molecular targets[1][7][8].
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