Drug intelligence / Profile preview

Ligandrol

Development stage
Phase 2
Lead developer
Viking Therapeutics
Modality
Small Molecules
Administration
Oral
01

Overview

Ligandrol is a selective androgen receptor modulator (SARM) developed for the treatment of muscle wasting, osteoporosis, and muscle atrophy, particularly in people with hip fracture. It acts by selectively binding to androgen receptors in skeletal muscle and bone tissue, mimicking the effects of testosterone but with fewer side effects than traditional anabolic steroids. This binding initiates gene expression changes that promote muscle repair and growth. Ligandrol has been studied as an investigational drug for conditions such as cancer-related cachexia, hypogonadism, and breast cancer; however, development for some indications has been discontinued. It is taken orally and remains unapproved for medical use by regulatory agencies[2][4][5].

Brand names
LigandrolAnabolicum
Other names
LigandrolLGD4033LGD-4033LGD 4033
02

Targets

AR (Adrenergic receptors)

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