Drug intelligence / Profile preview

light green SF yellowish

Development stage
Discontinued
Modality
Small Molecules
Administration
Ophthalmic, Oral
01

Overview

Light green SF yellowish is a synthetic triarylmethane dye primarily used as a histological stain, especially for collagen fibers in tissue sections[1][2][3][4][6]. It is a standard counterstain in North American histology labs and is an essential component of Masson's trichrome and Papanicolaou stains, where it imparts blue-green coloration to the cytoplasm of certain cell types[1][6]. The dye typically exists as a disodium salt with maximum absorption at approximately 630 nm[1][2]. While it was once used as a food colorant, its use for this purpose has been discontinued due to low popularity and poor durability (tendency to fade)[2][6]. In clinical diagnostics, sterile strips containing the dye are sometimes used for detecting superficial corneal or conjunctival tissue changes[2]. Its mechanism of action involves selective binding to specific tissue components (such as collagen), enabling their visualization under microscopy.

Brand names
Greenglo
Other names
light green SF yellowish
02

Targets

ABCG2 (Breast cancer resistance protein)ABCB1 (P-glycoprotein)

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