Drug intelligence / Profile preview

Ligilactobacillus salivarius TCI153

Development stage
Unknown
Lead developer
TCI
Modality
Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Oral
01

Overview

Ligilactobacillus salivarius TCI153 is a probiotic strain developed by TCI Co., Ltd. for skin health and beauty applications. It operates through the gut-skin axis by modulating the gut microbiota and stimulating the endogenous production of sialic acid and epidermal growth factor (EGF). Clinical studies have demonstrated that oral supplementation with TCI153 significantly improves skin hydration, elasticity, and radiance while reducing melanin levels and transepidermal water loss (TEWL). The strain is typically formulated into "beauty-from-within" nutraceutical products, often in combination with vitamins and botanical extracts, and is commercially available in markets such as Taiwan.

Other names
Lactobacillus salivarius TCI153
02

Targets

SA (Sialic acid)

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