lime (citrus)

Lime (citrus) is an allergen extract derived from the fruit of the *Citrus aurantifolia* plant. It is primarily used as a diagnostic tool in clinical allergy testing, such as skin prick or intradermal tests, to identify hypersensitivity reactions in individuals suspected of having a lime allergy. The extract contains a complex mixture of proteins and other components from the lime fruit that can trigger an IgE-mediated allergic response in sensitized patients. When introduced to the skin, these allergens cross-link specific IgE antibodies on the surface of mast cells and basophils, leading to the release of inflammatory mediators like histamine and the formation of a measurable wheal-and-flare reaction. It is classified as a diagnostic biologic and is listed in the DrugBank database.

Other names

Citrus aurantifolia extractLime fruit extractLime allergen extract