Drug intelligence / Profile preview

Limonene

Development stage
Phase 2
Modality
Classical Binding Small Molecules → Small Molecules
Administration
Oral, Topical, Inhalation
01

Overview

Limonene is a naturally occurring chemical compound classified as a terpene and found predominantly in the peels of citrus fruits. It is widely used as a flavoring agent in foods and beverages and as a fragrance in cleaning products and cosmetics. In medicine and dietary supplements, limonene has been investigated for its potential anti-inflammatory, antioxidant, anticancer, antimicrobial (including antibacterial), gastroprotective (notably for GERD), hepatoprotective, immunomodulatory effects, and possible benefits for weight loss. Its mechanism of action includes altering cell membrane permeability in bacteria—leading to cell lysis—and possibly blocking carcinogen formation or inducing cancer cell death through oxidative stress pathways. However, most clinical evidence remains preliminary or insufficient[1][2][3][5][6].

Other names
limonènelimoneno

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