Drug intelligence / Profile preview

Lingguazhuqi Decoction

Development stage
Preclinical
Lead developer
Guangming Hospital of Traditional Chinese Medicine
Administration
Oral
01

Overview

Lingguazhuqi Decoction is a Traditional Chinese Medicine (TCM) formula that has been investigated for its efficacy in treating chronic diarrhea, specifically when associated with spleen insufficiency and phlegm-damp syndrome. It is administered orally and has shown promise in improving symptoms of chronic diarrhea. The specific herbal composition and detailed molecular mechanisms of action are not explicitly provided in the available context.

02

Targets

STAT3 (Signal Transducer and Activator of Transcription 3)MMP9 (Matrix metalloproteinase-9)STAT1 (Signal transducer and activator of transcription protein 1)CCND1 (Cyclin D1)HIF1A (Hypoxia-inducible factor 1-alpha)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)MAPK3 (Mitogen-activated protein kinase 1)

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