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Linggui Yangyuan Paste
- Development stage
- Phase 1
- Lead developer
- Xiyuan Hospital
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Linggui Yangyuan Paste is a Traditional Chinese Medicine (TCM) formulation developed by Xiyuan Hospital of the China Academy of Chinese Medical Sciences. It is primarily investigated for the treatment of male infertility, specifically targeting conditions such as asthenozoospermia (reduced sperm motility) and oligoasthenozoospermia (reduced sperm count and motility). As a TCM "paste" (Gao), it is a concentrated herbal extract intended to tonify the kidneys and improve reproductive health. The drug is currently being evaluated in multicenter, double-blind, randomized controlled trials to assess its efficacy in improving sperm parameters and its overall safety profile.
- Brand names
- Linggui Yangyuan paste
- Other names
- Linggui Yangyuan Gao灵龟养元膏
02
Targets
GSK3 (Glycogen synthase kinase 3 beta)LRP6 (Low-density lipoprotein receptor-related protein 6)SEPTIN4 (Septin-4)
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