Drug intelligence / Profile preview

LingGuiQiHua Granule

Development stage
Preclinical
Lead developer
Xiyuan Hospital
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

LingGuiQiHua Granule is a Traditional Chinese Medicine (TCM) formulation developed by Xiyuan Hospital of the China Academy of Chinese Medical Sciences. It is currently being investigated for the treatment of early-stage heart failure with preserved ejection fraction (HFpEF). The formulation is designed based on TCM principles, likely focusing on warming yang and transforming qi to address the underlying pathophysiology of cardiac dysfunction and fluid retention. It is being evaluated in a multicenter, randomized, double-blind, placebo-controlled exploratory clinical trial in China to determine its efficacy and safety in improving clinical outcomes for HFpEF patients.

Other names
LingGuiQiHuaLingGuiQiHua granules

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