lipirinen

Lipirinen is a proprietary composition consisting of phosphatidylserine (PS) conjugated to omega-3 fatty acids enriched with eicosapentaenoic acid (EPA). It is the active ingredient in medical foods such as Vayarin and Vay-R, which are orally administered for the clinical dietary management of complex lipid imbalances associated with attention deficit hyperactivity disorder (ADHD), particularly in children[1][2][4]. Lipirinen is designed to address specific lipid nutritional requirements that cannot be met by normal diet or standard dietary supplements. The mechanism of action involves providing essential long-chain polyunsaturated fatty acids important for brain and central nervous system development and function. Phosphatidylserine enriched with omega-3s has been shown to influence neuronal membrane integrity, signal transduction pathways (including regulation of sodium/calcium ATPase and protein kinase C), neurotransmitter activity (acetylcholine, dopamine, noradrenaline), and may increase brain glucose concentrations[2][3]. The exact mechanism by which Lipirinen exerts its effects in ADHD remains not fully understood.

Brand names

VayarinVay-R

Other names

phosphatidylserine-omega-3phosphatidylserine-omega3phosphatidylserine-omega 3PS-Omega-3PS-Omega3PS-Omega 3PS-EPA conjugate