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**LipoSkill Plus** is a proprietary autologous regenerative-medicine treatment developed by Bioscience Institute for soft-tissue augmentation and aesthetic tissue repair. The procedure harvests a small volume of a patient's adipose tissue, isolates and expands adipose-derived mesenchymal stem cells over approximately 3–4 weeks, and injects the expanded cells into the treatment area, commonly together with autologous fat graft material. The intended biological activity is tissue regeneration and support of graft integration through the paracrine activity of the implanted cells, including promotion of extracellular-matrix remodeling and local tissue repair. Bioscience Institute markets the treatment for body shaping, breast and buttock augmentation, facial reshaping, wrinkle and scar reduction, stretch-mark reduction, and penile soft-tissue augmentation.
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