liposomal bupivacaine + betamethasone

liposomal bupivacaine + betamethasone is a combination therapy being evaluated for the management of postoperative pain and the prevention of joint stiffness in patients undergoing arthroscopic surgery for rotator cuff injuries and shoulder adhesion. Liposomal bupivacaine is an extended-release formulation of the local anesthetic bupivacaine, which works by blocking voltage-gated sodium channels to inhibit the conduction of pain impulses. Compound betamethasone is a corticosteroid that provides both immediate and sustained anti-inflammatory effects by acting as an agonist at the glucocorticoid receptor. This combination is administered via intra-articular injection during surgery to provide long-lasting analgesia and reduce the inflammatory response that leads to postoperative adhesions. The Second Affiliated Hospital of Nanchang University is the primary developer conducting clinical trials for this specific therapeutic application.

Other names

Liposomal Bupivacaine + Compound Betamethasone InjectionLiposomal Bupivacaine + Compound Betamethasone