liposomal curcumin

Liposomal curcumin is a formulation in which the active compound, curcumin—a polyphenol derived from the root of *Curcuma longa* (turmeric)—is encapsulated within phospholipid-based vesicles called liposomes. This delivery system significantly enhances the bioavailability and absorption of otherwise poorly water-soluble and rapidly metabolized free-form curcumin. Mechanistically, curcumin exhibits antineoplastic, chemopreventive, antioxidant, anti-angiogenic, and anti-inflammatory activities. It modulates multiple molecular targets involved in inflammation and cancer progression by inhibiting nuclear factor kappa B (NF-κB) signaling pathways and downregulating pro-inflammatory cytokines. Preclinical studies have shown tumor growth reduction in pancreatic and colorectal cancers; clinical trials are ongoing for high-grade gliomas[1][6][8]. The improved pharmacokinetics of the liposomal form allow for both oral and intravenous administration with enhanced systemic exposure compared to standard extracts.

Brand names

Liposomal CurcuminLiposomal Curcumin (Amy Myers MD)Liposomal Curcumin (NutriDyn)Liposomal Curcumin (NuMedica)

Other names

liposome-encapsulated curcuminmicelle curcuminliquid liposomal curcumin