Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
liposomal diclofenac
- Development stage
- Preclinical
- Lead developer
- Virpax Pharmaceuticals
- Modality
- Small Molecules, Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems
- Administration
- Topical, Ophthalmic, Intraarticular, Oral
01
Overview
Liposomal diclofenac is a pharmaceutical formulation of diclofenac, a nonsteroidal anti-inflammatory drug (NSAID), encapsulated within liposomes. Diclofenac is widely recognized for its analgesic, anti-inflammatory, and antipyretic properties. Its primary mechanism of action involves the inhibition of cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzymes, which are crucial for the synthesis of prostaglandins, key mediators of pain, inflammation, and fever. The liposomal encapsulation aims to enhance the drug's therapeutic efficacy, improve its pharmacokinetic profile, and reduce systemic toxicity, particularly the gastrointestinal side effects commonly associated with conventional NSAID formulations. This advanced delivery system facilitates targeted and sustained release of diclofenac, especially when administered topically or intra-articularly, making it a promising approach for managing various pain and inflammatory conditions such as osteoarthritis and rheumatoid arthritis.
- Other names
- diclofenac sodium loaded liposomesdiclofenac liposomal gel
02
Targets
PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)
Beyond the preview
Go deeper on liposomal diclofenac.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on liposomal diclofenac.