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Lipovax-Fg115-TB
- Development stage
- Preclinical
- Lead developer
- Lipotek
- Modality
- Nanoparticles → Drug Delivery Systems, Vaccines & Immunotherapeutics
- Administration
- Intramuscular
01
Overview
Lipovax-Fg115-TB is a preclinical lipid-based vaccine candidate developed by the Australian biotechnology company Lipotek, in collaboration with PT Bio Farma and academic partners. The vaccine is designed for the prevention or treatment of tuberculosis (TB) and utilizes Lipotek's proprietary Lipovax platform. This platform involves the use of liposomes or lipid-based nanoparticles to deliver specific antigens (in this case, the Fg115 antigen) and adjuvants, aiming to enhance the immune system's recognition and response to *Mycobacterium tuberculosis*. The program has demonstrated proof-of-concept in preclinical studies.
02
Targets
Mycobacterium tuberculosis-specific T-cell receptor (Mtb-specific TCR)Antigen-specific B-cell receptor recognizing Mycobacterium tuberculosis epitopes (Mtb-specific BCR)TLR5
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