Listerine Total Care Zero

Listerine Total Care Zero is a marketed, over-the-counter, alcohol-free anticavity mouthwash developed by Johnson & Johnson. Its primary active ingredient is sodium fluoride (0.02%), which works by promoting the remineralization of tooth enamel and increasing its resistance to acid-mediated decay. The formulation also includes a signature blend of essential oils—eucalyptol, thymol, menthol, and methyl salicylate—which provide antimicrobial activity against cariogenic oral bacteria and help freshen breath. As an alcohol-free rinse, it is designed to provide the benefits of a multi-action mouthwash without the intense taste associated with ethanol-containing formulations. It is indicated for the prevention of dental caries and has been utilized as a standard marketed comparator in clinical studies evaluating oral hygiene products.

Brand names

Listerine Total Care Zero

Other names

Listerine Total Care Zero Alcohol-Free Mouthwash