Drug intelligence / Profile preview

lithium liposome

Development stage
Preclinical
Lead developer
Laboratoire Dermatologique ACM
Modality
Small Molecules, Liposomes → Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems
Administration
Topical
01

Overview

Lithium liposome is a cosmetic product formulated with lithium encapsulated within liposomes, currently under evaluation for the repigmentation of vitiligo. The liposomal delivery system is designed to enhance the penetration of lithium into the skin, improving its bioavailability and targeted action. Lithium, as the active ingredient, is understood to exert its effects, in part, through the inhibition of Glycogen Synthase Kinase-3 beta (GSK-3β). This mechanism is believed to promote melanocyte proliferation and migration, which are crucial processes for restoring pigmentation in vitiligo, a condition characterized by the loss of melanocytes. The product is being developed by Laboratoire Dermatologique ACM.

Other names
Lithium liposome
02

Targets

GSK3 (Glycogen synthase kinase 3 beta)

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