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Liuwei Tangshen Decoction

Development stage: Unknown
Lead developer: Beijing Hospital
Administration: Oral

Overview

Liuwei Tangshen Decoction (LWTSD) is a Traditional Chinese Medicine (TCM) herbal formula developed by Beijing Hospital specifically for the treatment of diabetic kidney disease (DKD). The decoction is an optimized prescription based on classical TCM principles, designed to address the "Qi and Yin deficiency" pattern commonly observed in early-stage diabetic nephropathy. It aims to reduce urinary albumin excretion, protect podocytes, and inhibit the progression of renal fibrosis. Clinical research, including the study registered under ChiCTR2400088292, focuses on evaluating its efficacy and safety as an adjunctive therapy to standard diabetic care in patients with early diabetic nephropathy.

Other names: Liuwei Tangshen formula

Targets

NF-κBTGFB1 (Transforming growth factor Beta-1 proprotein)

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